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In clinical trials this translates into larger average weight loss than mono-agonist GLP-1s in adults with obesity
V.et al (2025)
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These findings indicate that persistent adipose tissue remodeling occurs irrespective of the magnitude of weight loss, reinforcing the concept of tissue-specific regulation of inflammation and fibrosis
Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method or add a barrier method of contraception for 4 weeks after initiation and for 4 weeks after each dose escalation with it
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